Hilary Jones...Drummer

 

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Dosage

solution %
same as mg/cc

Examples

1)  Prepare a 1% solution of Brevital (500 mg of powder in bottle).  How many mL of sterile water will you use?

 

Answer:  First convert 1% solution to mg/cc.  A 1% solution is the same as 1000 milligrams in 100 cc or 10mg/cc.

Percent solutions all are 1000mg/100cc.  For example a 2% = 20mg/cc, 5% = 50mg/cc, 5.5% = 55mg/cc, etc...

Now you have all the information needed to use the IV dosage calculator.  This problem is the same as the doctor ordering a 500 mg IV bag of Brevital:  500 mg = dose ordered, 10mg = dose available, and 1cc = mL available (the last two values come from 10mg/cc obtained above).  The answer is 50cc.

2)  1.4cc of ½% tetracaine (Pontocaine) was given in a subarachoid block.  How many mg were given?

 

Answer: First convert ½% to mg/cc.  A 0.5% solution is the same as 500mg/100cc (5mg/cc).

Now you have all the information needed to use the mL/hr to dose/hr calculator.  1.4 cc = mL given, 5mg = dose available, and 1cc = mL available.  So 7mg of tetracaine were given.

Epinephrine Solutions

Epinephrine vials are also labeled by concentration of a ratio of medication per mL.  For example, a solution may be labeled as 1:100,000.  This concentration represents 1000mg/100,000mL or 0.01mg/mL.  Here are some others:

CONCENTRATION DOSAGE EQUIVALANCE PERCENT
1:1,000 1mg/mL 0.1%
1:10,000 0.1mg/mL 0.01%
1:100,000 0.01mg/mL 0.001%
1:200,000 0.005mg/mL 0.0005%

Example

How many mg of epinephrine are in 5cc of a 1:10,000 solution?

 

Answer:  First convert 1:10,000 into mg/cc.
1:10,000 = 1000mg/10,000cc = 0.1mg/cc

Next use the IV dose given calculator.  5cc = mL given, 0.1mg = dosage available, and 1cc = mL available.  The answer is 0.5 mg of epinephrine were given.

 

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